Refs/PM20943270.corr

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PM20943270.corr
TAG! Jewk10b

PM20943270.mdl
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AB: OBJECTIVES: To describe prevalence of childhood experiences of adversity in rural South African youth and their associations with health outcomes. METHODS: We analyzed questionnaires and blood specimens collected during a baseline survey for a cluster randomized controlled trial of a behavioral intervention, and also tested blood HIV and herpes simplex type 2 virus at 12- and 24-month follow up; 1,367 male and 1,415 female volunteers were recruited from 70 rural villages. RESULTS: Both women and men before 18 had experienced physical punishment (89.3% and 94.4%), physical hardship (65.8% and 46.8%), emotional abuse (54.7% and 56.4%), emotional neglect (41.6% and 39.6%), and sexual abuse (39.1% and 16.7%). Incident HIV infections were more common in women who experienced emotional abuse (IRR 1.96, 95% CI 1.25, 3.06, p=.003), sexual abuse (IRR 1.66 95% CI 1.04, 2.63, p=.03), and physical punishment (IRR 2.13 95% CI 1.04, 4.37, p=.04). Emotional neglect in women was associated with depression (aOR 1.82, 95% CI 1.15, 2.88, p=.01), suicidality (aOR 5.07, 95% CI 2.07, 12.45, p<.0001), alcohol abuse (aOR 2.17, 95% CI .99, 4.72, p=.05), and incident HSV2 infections (IRR 1.62, 95% CI 1.01, 2.59, p=.04). In men emotional neglect was associated with depression (aOR 3.41, 95% CI 1.87, 6.20, p<.0001) and drug use (aOR 1.98, 95% CI 1.37, 2.88, p<.0001). Sexual abuse was associated with alcohol abuse in men (aOR 3.68, 95% CI 2.00, 6.77, p<.0001) and depression (aOR 2.16, 95% CI 1.34, 3.48, p=.002) and alcohol abuse in women (aOR 3.94, 95% CI 1.90, 8.17, p<.0001). PRACTICE IMPLICATIONS: Childhood exposure to adversity is very common and influences the health of women and men. All forms of adversity, emotional, physical and sexual, enhance the risk of adverse health outcomes in men and women. Prevention of child abuse need to be included as part of the HIV prevention agenda in sub-Saharan Africa. Interventions are needed to prevent emotional, sexual, and physical abuse and responses from health and social systems in Africa to psychologically support exposed children must be strengthened.
AD: Gender and Health Research Unit, Medical Research Council, South Africa.
AID: S0145-2134(10)00225-5 [pii] #AND# 10.1016/j.chiabu.2010.05.002 [doi]
AU: Jewkes RK #AND# Dunkle K #AND# Nduna M #AND# Jama PN #AND# Puren A
CI: Copyright (c) 2010 Elsevier Ltd. All rights reserved.
CRDT: 2010/10/15 06:00
DA: 20101115
DCOM: 20110228
DEP: 20101012
DP: 2010 Nov
EDAT: 2010/10/15 06:00
FAU: Jewkes, Rachel K #AND# Dunkle, Kristin #AND# Nduna, Mzikazi #AND# Jama, P Nwabisa #AND# Puren, Adrian
GR: MH 64882-01/MH/NIMH NIH HHS/United States #AND# MH 64882-04S1A1/MH/NIMH NIH HHS/United States
IP: 11
IS: 1873-7757 (Electronic) #AND# 0145-2134 (Linking)
JID: 7801702
JT: Child abuse & neglect
LA: eng
LID: 10.1016/j.chiabu.2010.05.002 [doi]
LR: 20131021
MH: Adolescent #AND# Adult #AND# Alcohol-Related Disorders/diagnosis/epidemiology/*psychology #AND# Child Abuse/*psychology/*statistics & numerical data #AND# Cluster Analysis #AND# Depressive Disorder/epidemiology/*psychology #AND# Enzyme-Linked Immunosorbent Assay #AND# Female #AND# HIV Infections/blood/epidemiology/*etiology/prevention & control #AND# HIV-1 #AND# Herpes Genitalis/epidemiology/*etiology #AND# Herpesvirus 2, Human #AND# Humans #AND# Male #AND# Prevalence #AND# Questionnaires #AND# Rural Population #AND# Sex Distribution #AND# South Africa/epidemiology #AND# Substance-Related Disorders #AND# Young Adult
MHDA: 2011/03/01 06:00
MID: NIHMS233828
OID: NLM: NIHMS233828 #AND# NLM: PMC2981623
OWN: NLM
PG: 833-41
PHST: 2009/06/25 [received] #AND# 2009/11/12 [revised] #AND# 2010/05/31 [accepted] #AND# 2010/10/12 [aheadofprint]
PL: England
PMC: PMC2981623
PMID: 20943270
PST: ppublish
PT: Journal Article #AND# Randomized Controlled Trial #AND# Research Support, N.I.H., Extramural #AND# Research Support, Non-U.S. Gov't
SB: IM
SO: Child Abuse Negl. 2010 Nov;34(11):833-41. doi: 10.1016/j.chiabu.2010.05.002. Epub 2010 Oct 12. 
STAT: MEDLINE
TA: Child Abuse Negl
TAG: Jewk10b
TI: Associations between childhood adversity and depression, substance abuse and HIV and HSV2 incident infections in rural South African youth.
VI: 34